This laboratory focuses on CNS circuits and cellular systems that participate and regulate these states in the brains of individuals with severe mental illness. Using a variety of molecular, anatomical, behavioral and pharmacological approaches, it is possible to focus on key circuits and molecules of interest. Our research group heavily collaborates with Dr. Huda Akil and is part of the Pritzker Neuropsychiatric Research Consortium that investigates depression, bipolar disease and schizophrenia in postmortem human brain. Research tools in our laboratory include the use of a range of molecular, genetic, anatomical, behavioral and clinical approaches in a highly interdisciplinary environment.